Sermorelin
Sermorelin is a synthetic GHRH analogue of 29 amino acids derived from the active N-terminal fragment of growth hormone-releasing hormone (GHRH 1-29), studied in GH-axis research for its role in pulsing pituitary GH secretion via the GHRH-R receptor.
A GHRH analogue studied for endogenous growth hormone stimulation — investigated in body-composition, sleep, and healthy-aging contexts.
- Availability
- Ships within 1 business day
- Storage
- Store 2–8 °C. Use reconstituted vial within 14 days.
- Ships from
- European fulfilment centre, cold-chain express
Lab proof, by batch
- Tested independently, by batch
- Certificate of analysis available
- Purity and identity on record
Endogenous Growth Hormone Research.
Sermorelin (CAS 86168-78-7) is the biologically active N-terminal fragment of GHRH, comprising the first 29 amino acids. Research has examined its role in stimulating pituitary GH secretion, elevating IGF-1 levels, and improving sleep architecture. Formula C149H246N44O42S, MW 3357.93 g/mol.
- — Vittone et al. — Sermorelin effects on GH pulse amplitude and body composition
- — Walker et al. — GHRH analogue effects on IGF-1 and sleep architecture
Research context only. Not medical advice. Consult a qualified clinician before use.
- 5 mg lyophilised powder per vial
- Reconstitute with bacteriostatic water before use
- Store lyophilised at 2–8 °C, protect from light
- Once reconstituted, refrigerate and use within 14 days
- One 5 mg lyophilised Sermorelin vial
- Tamper-evident cap with batch-coded label
- Storage card with reconstitution guidance
What the research reports about this molecule.
Classic parameters from peer-reviewed literature. Not human dosing guidance — read alongside the PubMed references on /learn.
- Sequence
- GHRH 1-29 truncation (29 amino acids)
- Molecular weight
- 3358 Da
- Mechanism
- Pulses GH via GHRH-R receptor
- Research domain
- GH-axis research
- Reconstitution
- Bacteriostatic water, USP
- Storage
- Long-term -20°C lyophilised; -80°C for >12 months; reconstituted 2-8°C, ≤4 weeks
Simple, deliberate steps — not a protocol.
These are practical handling notes. Dosing decisions stay between you and your clinician.
- 1
Reconstitute with 2 mL bacteriostatic water — swirl gently
- 2
Administer subcutaneously before sleep for pulsatile GH alignment under clinical protocol
- 3
Refrigerate reconstituted vial; use within 14 days
How-to-use guide
Read the research protocol
Concise reconstitution, dosing, and handling instructions.
Each release is matched with quality documentation through a documented verification path. Identity, purity, and composition test results sit on the product page before you buy.
Every batch is verified by an ISO/IEC 17025-accredited laboratory before release. Identity, purity, and documentation travel with the product — not behind a form.
Sensitive peptides ship in insulated insulated cold packaging with gel packs sized for a 48-hour transit window, tracked door to door.
Everything worth asking before you order.
Shipping, storage, quality, and when to speak to a clinician — without the runaround.
What proof of quality comes with my order?
Every batch ships with a batch code printed on the vial. The matching independent lab report — identity, purity, and composition — independently lab-tested results — is linked on the product page and also available from your order page after purchase.
Should I speak to a clinician before using a peptide?
We recommend it — especially if you are pregnant, nursing, managing a medical condition, or combining peptides with prescribed medication. Our product pages are educational. They are not medical advice and they do not replace a conversation with a qualified practitioner.
When will my order ship and arrive?
Orders placed before 14:00 CET Monday–Friday ship the same business day from our European fulfilment centre in The Hague, Netherlands. Standard tracked EU delivery arrives in 2–4 business days; express options are available at checkout.
Are research peptides banned by WADA?
Several research peptides we list — including BPC-157, TB-500, GHRPs, and IGF-1 LR3 — are listed on the WADA Prohibited List under classes S0 (unapproved substances) and S2 (peptide hormones and growth factors). They are prohibited at all times, in and out of competition.
How do I reconstitute a lyophilised peptide vial?
Bring both the lyophilised vial and the bacteriostatic water to room temperature, equalise pressure with a sterile vented needle, then inject the solvent slowly down the side of the vial. Swirl gently — never shake — until clear, and refrigerate at 2–8 °C.
How much bacteriostatic water should I add to my peptide vial?
The calculation is peptide mass (mg) ÷ desired concentration (mg/mL) = volume of bacteriostatic water in mL. For example, a 5 mg vial at 1 mg/mL needs 5 mL; at 2 mg/mL, 2.5 mL. Every Peptyds product page carries a suggested reconstitution volume tuned to the vial size.
How long does a reconstituted peptide stay stable in the fridge?
Most lyophilised peptides reconstituted with bacteriostatic water remain stable for 28–30 days at 2–8 °C, protected from light. A handful of short, fragile sequences — Epithalon among them — drop to roughly 14 days. Never freeze a reconstituted vial.
What side effects are most commonly reported across peptide research?
Across published trials and case series, the most frequent reported events are injection-site reactions (redness, induration, transient discomfort), headache, mild nausea, and temporary fatigue. GLP-1 and dual-agonist class peptides add dose-dependent gastrointestinal effects.
Who should not use peptides?
Peptides are not appropriate for anyone who is pregnant, nursing, planning conception, under 18, managing active cancer, or on immunosuppressants — and competitive athletes governed by WADA must avoid every peptide on the prohibited list. Anyone with a personal or family history of melanoma should specifically avoid melanocortin-receptor agonists.