Epithalon Premium
Epithalon is a synthetic tetrapeptide of 4 amino acids (Ala-Glu-Asp-Gly) derived from a pineal-gland extract, studied in chronobiology and ageing research for its role in modulating telomerase activity and circadian pineal markers.
A tetrapeptide studied for its role in supporting telomerase activity and circadian rhythm — framed for long-horizon routines.
- ≥98% purity
- HPLC + MS verified
- ISO/IEC 17025 lab
- CoA per batch
For Research Use Only — Not for Human Consumption.
Sold strictly for in vitro laboratory research purposes.
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Epithalon Premium is out of stock. These are in stock.
Different compounds, matched on shared research goal and comparable cost per mg. They are not substitutes for one another — read the research on each page before you order.
- NAD+Cellular Energy & Redox ResearchSame goal · €0.69 / mgfrom €69
- SelankNootropic & Anxiolytic ResearchSame goal · €7.00 / mgfrom €35
- HGHEndocrinology & Cellular Regeneration ResearchSame goalfrom €29
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- Availability
- Delivered in 3–7 days (EU)
- Storage
- Store 2–8 °C. Keep from light.
- Ships from
- European fulfilment centre, tracked express
Lab proof, by batch
Batch EPI-25-014- Tested independently, by batch
- Certificate of analysis available
- Purity and identity on record
Tested by
Janoshik Analytical — ISO/IEC 17025 accredited
Telomerase & Longevity Research.
Epithalon (Ala-Glu-Asp-Gly) is a short peptide originally derived from pineal-gland extract. Research has examined telomerase signalling, melatonin rhythm, and age-related biomarkers. It is best understood as a long-horizon input, not a short-cycle intervention.
- — Khavinson et al. — tetrapeptide effects on telomerase activity
- — Anisimov et al. — preclinical studies on age-related biomarkers
Research context only. Not medical advice. Consult a qualified clinician before use.
- 10 mg lyophilised powder per vial
- Reconstitute with bacteriostatic water before use
- Store lyophilised vial at 2–8 °C, keep from light
- Once reconstituted, refrigerate and use within 14 days
- One 10 mg lyophilised Epithalon vial
- Tamper-evident cap with batch-coded label
- Storage card with reconstitution guidance
What the research reports about this molecule.
Classic parameters from peer-reviewed literature. Not human dosing guidance — read alongside the PubMed references on /learn.
- Sequence
- Tetrapeptide (Ala-Glu-Asp-Gly)
- Molecular weight
- 390 Da
- Mechanism
- Modulates telomerase activity and pineal circadian markers
- Research domain
- Chronobiology, ageing
- Reconstitution
- Bacteriostatic water, USP
- Storage
- Long-term -20°C lyophilised; -80°C for >12 months; reconstituted 2-8°C, ≤4 weeks
Simple, deliberate steps — not a protocol.
These are practical handling notes. Dosing decisions stay between you and your clinician.
- 1
Reconstitute with 2 mL bacteriostatic water — swirl gently
- 2
Draw the dose agreed with your clinician using a fine-gauge syringe
- 3
Refrigerate the reconstituted vial; use within 14 days
How-to-use guide
Read the research protocol
Concise reconstitution, dosing, and handling instructions.
Reconstitution calculator
Research use onlySyringe
Peptide in vial
Bacteriostatic water
Concentration5 mg/mL
Target dose
Pull syringe to
5
units · 0.05 mL
Concentration
5
mg/mL
Doses per vial
40
doses
U-50 2.5 · U-40 2 units
For laboratory research calculation only. Not medical or dosing advice, and not for human or veterinary use.
Batch report
Batch EPI-25-014
Analysed 14 Feb 2025
Sample received 10 Feb 2025
What the certificate says
- Purity exceeds the declared ≥ 98 % specification.
- Identity confirmed against a characterised peptide reference.
- Heavy metals within permitted single-dose limits (ICH Q3D).
- Tested by
- Janoshik Analytical
- Accreditation
- ISO/IEC 17025 accredited
- CAS
- 307297-39-8
- Formula
- C14H22N4O9
- M.W.
- 390.35 g/mol
- Lab region
- European Union
Results, by method
| Method | Analyte | Result |
|---|---|---|
| HPLC-UV | Peptide purity Spec ≥ 98.00% | 98.72%Pass |
| LC-MS | Identity (molecular mass) Spec 390.35 g/mol ± 0.5 | 390.4 g/mol (confirmed)Pass |
| Karl Fischer | Residual moisture Spec ≤ 6.0% | 3.1%Pass |
| LAL | Bacterial endotoxins Spec ≤ 0.25 EU/mg | < 0.05 EU/mgPass |
| ICP-MS | Heavy metals (Pb, Cd, As, Hg) Spec ICH Q3D limits | Below PDEPass |
Methods follow USP and European Pharmacopoeia references. Identity confirmed against a characterised reference standard.
Others researching Healthy Aging also compare
- Epithalon PremiumThis pagePurity: ≥98%Sizes: 10 mgPrice / mg: €6.90 / mg
- NAD+Sizes: 100 mgPrice / mg: €0.69 / mg
- SelankSizes: 5 mgPrice / mg: €7.00 / mg
- HGHSizes: 10 ui
Each release is matched with quality documentation through a documented verification path. Identity, purity, and composition test results sit on the product page before you buy.
Every batch is verified by an ISO/IEC 17025-accredited laboratory before release. Identity, purity, and documentation travel with the product — not behind a form.
Sensitive peptides ship in insulated cold packaging with gel packs sized for a 48-hour transit window, tracked door to door.
Everything worth asking before you order.
Shipping, storage, quality, and when to speak to a clinician — without the runaround.
How much scientific detail is on each product page?
Each page opens with a clear purpose line and the testing behind it, then expands into research notes, dosing specifications, and linked peer-reviewed studies for readers who want more depth. You decide how deep you go.
What proof of quality comes with my order?
Every batch ships with a batch code printed on the vial. The matching independent lab report — showing identity, purity, and composition — is linked on the product page and stays on your order page after purchase.
Should I speak to a clinician before using a peptide?
We recommend it — especially if you are pregnant, nursing, managing a medical condition, or combining peptides with prescribed medication. Our product pages are educational. They are not medical advice and they do not replace a conversation with a qualified practitioner.
Are peptides safe long-term?
Honestly: it depends on the molecule. EMA-approved peptide drugs (semaglutide, tirzepatide, tesamorelin, thymalfasin in some jurisdictions) have multi-year safety datasets. Unapproved research peptides — BPC-157, TB-500, Melanotan II, Epithalon — have limited or no long-term human data.
How do I reconstitute a lyophilised peptide vial?
Bring both the lyophilised vial and the bacteriostatic water to room temperature, equalise pressure with a sterile vented needle, then inject the solvent slowly down the side of the vial. Swirl gently — never shake — until clear, and refrigerate at 2–8 °C.
How much bacteriostatic water should I add to my peptide vial?
The calculation is peptide mass (mg) ÷ desired concentration (mg/mL) = volume of bacteriostatic water in mL. For example, a 5 mg vial at 1 mg/mL needs 5 mL; at 2 mg/mL, 2.5 mL. Every Peptyds product page carries a suggested reconstitution volume tuned to the vial size.
How long does a reconstituted peptide stay stable in the fridge?
Most lyophilised peptides reconstituted with bacteriostatic water remain stable for 28–30 days at 2–8 °C, protected from light. A handful of short, fragile sequences — Epithalon among them — drop to roughly 14 days. Never freeze a reconstituted vial.
What side effects are most commonly reported across peptide research?
Across published trials and case series, the most frequent reported events are injection-site reactions (redness, induration, transient discomfort), headache, mild nausea, and temporary fatigue. GLP-1 and dual-agonist class peptides add dose-dependent gastrointestinal effects.
Who should not use peptides?
Peptides are not appropriate for anyone who is pregnant, nursing, planning conception, under 18, managing active cancer, or on immunosuppressants — and competitive athletes governed by WADA must avoid every peptide on the prohibited list. Anyone with a personal or family history of melanoma should specifically avoid melanocortin-receptor agonists.