PT-141
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide that acts as a melanocortin receptor agonist (MC3R and MC4R), studied in the literature for its role in central-nervous-system pathways rather than peripheral vascular signalling.
Bremelanotide — a melanocortin receptor agonist studied for its role in sexual arousal pathways through central nervous system signalling rather than vascular mechanisms.
- Availability
- Ships within 1 business day
- Storage
- Store 2–8 °C. Reconstitute before use.
- Ships from
- European fulfilment centre, cold-chain express
Lab proof, by batch
- Tested independently, by batch
- Certificate of analysis available
- Purity and identity on record
Central Melanocortin Receptor Research.
PT-141 (Bremelanotide, CAS 189691-06-3) is a cyclic heptapeptide that activates MC3R and MC4R receptors in the CNS. Research has focused on its role in sexual motivation and arousal in both male and female subjects, independent of vascular action. Formula C50H68N14O10, MW 1025.18 g/mol. Use under clinical guidance.
- — Clayton et al. — Bremelanotide and female sexual dysfunction: RECONNECT trial
- — Safarinejad & Hosseini — PT-141 effects on male erectile function in a controlled study
Research context only. Not medical advice. Consult a qualified clinician before use.
- 5 mg lyophilised powder per vial
- Reconstitute with bacteriostatic water before use
- Store lyophilised at 2–8 °C, keep from light
- Once reconstituted, refrigerate and use within 30 days
- One 5 mg lyophilised PT-141 vial
- Tamper-evident cap with batch-coded label
- Storage and clinician-consultation card
Simple, deliberate steps — not a protocol.
These are practical handling notes. Dosing decisions stay between you and your clinician.
- 1
Reconstitute with 2 mL bacteriostatic water — swirl gently
- 2
Administer subcutaneously 45–60 minutes before intended use as directed by your clinician
- 3
Refrigerate reconstituted vial; use within 30 days
How-to-use guide
Read the research protocol
Concise reconstitution, dosing, and handling instructions.
Each release is matched with quality documentation through a documented verification path. Identity, purity, and composition test results sit on the product page before you buy.
Every batch is verified by an ISO/IEC 17025-accredited laboratory before release. Identity, purity, and documentation travel with the product — not behind a form.
Sensitive peptides ship in insulated insulated cold packaging with gel packs sized for a 48-hour transit window, tracked door to door.
Everything worth asking before you order.
Shipping, storage, quality, and when to speak to a clinician — without the runaround.
What proof of quality comes with my order?
Every batch ships with a batch code printed on the vial. The matching independent lab report — identity, purity, and composition — independently lab-tested results — is linked on the product page and also available from your order page after purchase.
Should I speak to a clinician before using a peptide?
We recommend it — especially if you are pregnant, nursing, managing a medical condition, or combining peptides with prescribed medication. Our product pages are educational. They are not medical advice and they do not replace a conversation with a qualified practitioner.
When will my order ship and arrive?
Orders placed before 14:00 CET Monday–Friday ship the same business day from our European fulfilment centre in The Hague, Netherlands. Standard tracked EU delivery arrives in 2–4 business days; express options are available at checkout.
What does "research only" actually mean on a peptide label?
Research-only means the compound has not been approved by the EMA or any national medicines authority for medical use, and is sold solely for in-vitro and laboratory research. It is not a supplement, a cosmetic, or a medicine, and it carries no claims for human consumption.
How is PT-141 different from PDE-5 inhibitors like sildenafil?
PT-141 (bremelanotide) is a melanocortin-receptor agonist that acts centrally on MC3R and MC4R pathways in the hypothalamus, modulating sexual arousal signalling. PDE-5 inhibitors such as sildenafil act peripherally on vascular smooth muscle. Bremelanotide is FDA-approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women; in the EU it is not approved.
How long do PT-141's effects last in published research?
Published pharmacokinetic studies report a plasma half-life of roughly 2.7 hours for bremelanotide, with measurable receptor effects in clinical trials spanning approximately 6–12 hours after a single subcutaneous dose.
What's the difference between a prescription peptide and a research peptide?
A prescription peptide (e.g. Wegovy, Mounjaro, Vyleesi, Zadaxin in the relevant jurisdictions) has been through EMA or national-authority review, carries an authorised indication, and is dispensed by a pharmacy against a script. A research peptide is a reference-grade compound sold for laboratory use only.
How do I reconstitute a lyophilised peptide vial?
Bring both the lyophilised vial and the bacteriostatic water to room temperature, equalise pressure with a sterile vented needle, then inject the solvent slowly down the side of the vial. Swirl gently — never shake — until clear, and refrigerate at 2–8 °C.
How much bacteriostatic water should I add to my peptide vial?
The calculation is peptide mass (mg) ÷ desired concentration (mg/mL) = volume of bacteriostatic water in mL. For example, a 5 mg vial at 1 mg/mL needs 5 mL; at 2 mg/mL, 2.5 mL. Every Peptyds product page carries a suggested reconstitution volume tuned to the vial size.
How long does a reconstituted peptide stay stable in the fridge?
Most lyophilised peptides reconstituted with bacteriostatic water remain stable for 28–30 days at 2–8 °C, protected from light. A handful of short, fragile sequences — Epithalon among them — drop to roughly 14 days. Never freeze a reconstituted vial.
What side effects are most commonly reported across peptide research?
Across published trials and case series, the most frequent reported events are injection-site reactions (redness, induration, transient discomfort), headache, mild nausea, and temporary fatigue. GLP-1 and dual-agonist class peptides add dose-dependent gastrointestinal effects.
Who should not use peptides?
Peptides are not appropriate for anyone who is pregnant, nursing, planning conception, under 18, managing active cancer, or on immunosuppressants — and competitive athletes governed by WADA must avoid every peptide on the prohibited list. Anyone with a personal or family history of melanoma should specifically avoid melanocortin-receptor agonists.